Pazopanib, a promising option for the treatment of aggressive fibromatosis

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Pazopanib, a promising option for the treatment of aggressive fibromatosis

Desmoid tumour/aggressive fibromatosis (DT/AF) is a rare soft-tissue neoplasm that is locally aggressive but does not metastasize. There is no standard systemic treatment for symptomatic patients, although a number of agents are used. Tyrosine kinase inhibitors have recently been reported to show useful activity. We reviewed our bi-institutional (Royal Marsden Hospital, Cambridge University Hos...

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Aggressive Fibromatosis of Parapharyngeal Space: a rare case report

Aggressive fibromatosis also known as extra abdominal desmoid tumor is an uncommon benign tumor of soft tissue origin with fibroblastic proliferationSince the tumor is locally aggressive, the lesion may be misdiagnosed as low -grade fibrosarcoms. It accounts for 0.03% - 0.1% of all body tumors and 3% of all soft tissue tumors. Only 10% to 15% of these lesions occur in head and neck, usually in ...

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Aggressive Fibromatosis of Parapharyngeal Space: a rare case report

Aggressive fibromatosis also known as extra abdominal desmoid tumor is an uncommon benign tumor of soft tissue origin with fibroblastic proliferationSince the tumor is locally aggressive, the lesion may be misdiagnosed as low -grade fibrosarcoms. It accounts for 0.03% - 0.1% of all body tumors and 3% of all soft tissue tumors. Only 10% to 15% of these lesions occur in head and neck, usually ...

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Idiopathic gingival fibromatosis with unilateral aggressive periodontitis: A case report

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Aggressive Fibromatosis: Evidence for a Stable Phase

Purpose. Aggressive fibromatosis (AF) is an uncommon locally infiltrating benign disease of soft tissue for which treatment comprises complete surgical resection. Radiotherapy can be given postoperatively if the margin is incompletely resected. If the tumour is inoperable radiotherapy provides an alternative treatment. Hormone therapy and cytotoxic chemotherapy have also been used for unresecta...

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ژورنال

عنوان ژورنال: Anti-Cancer Drugs

سال: 2017

ISSN: 0959-4973

DOI: 10.1097/cad.0000000000000474